Breast cancer

The PBS subsidises lapatinib, pertuzumab, trastuzumab, trastuzumab deruxtecan and trastuzumab emtansine for patients with breast cancer.

Please note: You’ll get an immediate assessment when you request PBS authorities online.

Patient eligibility

The Pharmaceutical Benefits Scheme (PBS) subsidises treatment with lapatinib, pertuzumab, trastuzumab, trastuzumab deruxtecan and trastuzumab emtansine under the National Health Act 1953, section 85 and section 100 for patients with breast cancer.

Patients must be eligible for the PBS and meet the relevant restriction criteria.

The Schedule of Pharmaceutical Benefits on the PBS website outlines the restrictions for prescribing lapatinib, pertuzumab, trastuzumab, trastuzumab deruxtecan and trastuzumab emtansine.

Section 100 arrangements

Pertuzumab, trastuzumab i.v., trastuzumab deruxtecan and trastuzumab emtansine

These items are only PBS-subsidised for non-admitted patients, day admitted patients, or patients on discharge who are attending:

  • an approved private hospital
  • a public participating hospital
  • a public hospital.

These items aren’t PBS-subsidised for public hospital in-patients. You must include the hospital name and provider number on the authority application form.

Authority applications

Trastuzumab

All PBS-subsidised treatment with trastuzumab is Authority Required (Streamlined). You don’t need authority approval from us for the listed quantities and repeats.

Early HER2 positive breast cancer

Applying for initial treatment

Applications for initial authority approval to prescribe PBS-subsidised trastuzumab emtansine to treat early HER2 positive breast cancer can be made either in:

All written applications must include:

Applying for continuing treatment

Applications for continuing authority approval to prescribe PBS-subsidised trastuzumab emtansine to treat early HER2 positive breast cancer can be made either:

Metastatic (Stage IV) HER2 positive breast cancer

Applying for initial treatment

Applications for initial authority approval to prescribe PBS-subsidised lapatinib to treat metastatic (Stage IV) HER2 positive breast cancer can be made either in:

All written applications must include:

Applications for initial authority approval to prescribe PBS-subsidised pertuzumab, trastuzumab deruxtecan or trastuzumab emtansine to treat metastatic (Stage IV) HER2 positive breast cancer can be made either:

Applying for continuing treatment

Applications for continuing authority approval to prescribe PBS-subsidised pertuzumab, trastuzumab deruxtecan or trastuzumab emtansine to treat metastatic (Stage IV) HER2 positive breast cancer can be made either:

Continuing PBS-subsidised treatment with lapatinib is Authority Required (Streamlined). You don’t need authority approval from us for the listed quantities and repeats.

Unresectable and/or metastatic HER2-low breast cancer

Applications for authority approval to prescribe PBS-subsidised trastuzumab deruxtecan to treat unresectable and/or metastatic HER2-low breast cancer can be made either:

More information

Call the PBS Complex Drugs Programs enquiry line for more information.

Page last updated: 1 September 2024.
QC 32471